Resveratrol

Ingredient

Resveratrol

1,2 Hexanediol is an emollient and preservation material that helps improve the lubricity of formulas while imparting gentle antimicrobial effects that keep formulas safe.

Common Name

Resveratrol

Category

Antioxidant

Benefits

Anti-aging

Anti-inflammatory

Skin-protective

Antioxidant

Performance Rating

Very Good

Chemical Structure

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural polyphenolic compound with a molecular formula of C14H12O3. It consists of two phenol rings connected by a double styrene bond.

Quick Summary Benefits

Potent antioxidant protection

Reduces signs of aging

Calms inflammation

Enhances skin's natural defense

Promotes collagen production

Use & Background in Skincare

Resveratrol has gained popularity in skincare due to its powerful antioxidant properties. It is derived from various plants, including grapes, berries, and peanuts. Resveratrol is known for its ability to protect skin cells from environmental damage and slow down the aging process.

Detailed Description

Resveratrol is a naturally occurring polyphenolic compound that has garnered significant attention in the skincare industry for its potent antioxidant and anti-aging properties. This powerful molecule is found in various plants, most notably in the skin of red grapes, and has been the subject of numerous scientific studies for its potential health and skincare benefits.

The primary mechanism of action for resveratrol in skincare is its ability to neutralize free radicals and reduce oxidative stress. Free radicals are unstable molecules that can damage cellular structures, including DNA, proteins, and lipids, leading to premature aging and various skin concerns. Resveratrol acts as a scavenger, effectively neutralizing these harmful molecules and protecting the skin from oxidative damage [1].

In addition to its antioxidant properties, resveratrol has been shown to have anti-inflammatory effects on the skin. A study published in the Archives of Dermatological Research demonstrated that resveratrol could inhibit the production of inflammatory mediators in human skin cells, potentially reducing redness and irritation associated with various skin conditions [2]. Furthermore, research has indicated that resveratrol may enhance the production of collagen and elastin, two essential proteins for maintaining skin elasticity and firmness [3].

Clinical studies have also suggested that resveratrol may have photoprotective properties, helping to defend the skin against UV-induced damage. A randomized, double-blind study published in the Journal of Cosmetic Dermatology found that topical application of resveratrol significantly improved various parameters of photo-aged skin, including wrinkle depth, skin elasticity, and pigmentation [4]. These findings highlight the potential of resveratrol as a key ingredient in anti-aging and sun-protective skincare formulations.

Comedogenicity

1 (Low) - Resveratrol is generally considered non-comedogenic [5].

Sustainability Notes

Resveratrol can be sustainably sourced from various plant materials, including grape byproducts from the wine industry. Some companies are exploring biotechnology methods to produce resveratrol more sustainably through fermentation processes.

How It's Made

Resveratrol is typically extracted from plant sources such as grape skins, Japanese knotweed, or berries. It can also be synthesized in laboratories to ensure purity and consistency in skincare formulations.

References

  • Ndiaye M, Philippe C, Mukhtar H, Ahmad N. The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges. Arch Biochem Biophys. 2011;508(2):164-170. doi:10.1016/j.abb.2010.12.030
  • Pastore S, Lulli D, Fidanza P, et al. Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system. Antioxid Redox Signal. 2012;16(4):314-328. doi:10.1089/ars.2011.4053
  • Ratz-Łyko A, Arct J. Resveratrol as an active ingredient for cosmetic and dermatological applications: a review. J Cosmet Laser Ther. 2019;21(2):84-90. doi:10.1080/14764172.2018.1469767
  • Farris P, Krutmann J, Li YH, McDaniel D, Krol Y. Resveratrol: a unique antioxidant offering a multi-mechanistic approach for treating aging skin. J Drugs Dermatol. 2013;12(12):1389-1394.
  • Draelos ZD. Cosmeceuticals E-Book. Elsevier Health Sciences; 2014.