Glycerin

Ingredient

Glycerin

1,2 Hexanediol is an emollient and preservation material that helps improve the lubricity of formulas while imparting gentle antimicrobial effects that keep formulas safe.

Common Name

Glycerin

Category

Humectant

Benefits

Hydration

Protection

Smoothing

Healing

Performance Rating

Exceptional

Chemical Structure

Glycerin is a simple polyol compound with the chemical formula C3H8O3. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The molecule consists of a three-carbon backbone with each carbon bonded to a hydroxyl (-OH) group.

Quick Summary Benefits

  • Attracts and retains moisture in the skin
  • Improves skin barrier function
  • Enhances skin smoothness and softness
  • Helps in wound healing and skin repair
  • Suitable for all skin types, including sensitive skin

Use & Background in Skincare

Glycerin has been a staple in skincare for decades due to its excellent moisturizing properties. It is widely used in various skincare products, from moisturizers to cleansers, due to its ability to hydrate the skin without clogging pores or causing irritation.

Detailed Description

Glycerin, also known as glycerol, is a powerhouse ingredient in skincare due to its exceptional humectant properties. As a humectant, glycerin works by attracting water from the environment and deeper layers of the skin to the outer layer (stratum corneum), thereby increasing skin hydration [1]. This hydrating effect is not just superficial; glycerin has been shown to penetrate deep into the skin, providing long-lasting moisture retention.

The effectiveness of glycerin in skincare is backed by numerous scientific studies. Research has shown that glycerin can improve skin barrier function, increase skin hydration, and enhance skin elasticity [2]. A study published in the British Journal of Dermatology found that glycerin was more effective than other humectants, including hyaluronic acid and sorbitol, in increasing skin hydration and reducing transepidermal water loss [3].

Beyond its hydrating properties, glycerin has been found to have protective and healing effects on the skin. It can help shield the skin from irritants and environmental stressors, making it particularly beneficial for sensitive or compromised skin [4]. Additionally, glycerin has been shown to accelerate wound healing processes and improve skin barrier recovery, which is crucial for maintaining healthy, resilient skin [5].

Comedogenicity

Glycerin is rated 0 on the comedogenicity scale, meaning it is non-comedogenic and unlikely to clog pores or cause acne [6].

Sustainability Notes

Glycerin is considered a sustainable ingredient as it can be derived from both plant-based and synthetic sources. Many companies are now opting for plant-based glycerin to meet the growing demand for natural and eco-friendly skincare products.

How It's Made

Glycerin can be produced through various methods, including the saponification of triglycerides in vegetable oils or animal fats, or through synthetic processes using propylene. The most common method in skincare is the production from plant oils, particularly coconut and palm oils.

References

Fluhr JW, Darlenski R, Surber C. Glycerol and the skin: holistic approach to its origin and functions. Br J Dermatol. 2008;159(1):23-34. https://doi.org/10.1111/j.1365-2133.2008.08643.x

Lodén M, Wessman W. The influence of a cream containing 20% glycerin and its vehicle on skin barrier properties. Int J Cosmet Sci. 2001;23(2):115-119. https://doi.org/10.1046/j.1467-2494.2001.00060.x

Björklund S, Engblom J, Thuresson K, Sparr E. Glycerol and urea can be used to increase skin permeability in reduced hydration conditions. Eur J Pharm Sci. 2013;50(5):638-645. https://doi.org/10.1016/j.ejps.2013.04.022

Fluhr JW, Gloor M, Lehmann L, Lazzerini S, Distante F, Berardesca E. Glycerol accelerates recovery of barrier function in vivo. Acta Derm Venereol. 1999;79(6):418-421. https://doi.org/10.1080/000155599750010256

Sundaram H, Mackiewicz N, Burton E, Peno-Mazzarino L, Lati E, Meunier S. Pilot Comparative Study of the Topical Action of a Novel, Crosslinked Resilient Hyaluronic Acid on Skin Hydration and Barrier Function in a Dynamic, Three-Dimensional Human Explant Model. J Drugs Dermatol. 2016;15(4):434-441. https://jddonline.com/articles/pilot-comparative-study-of-the-topical-action-of-a-novel-crosslinked-resilient-hyaluronic-acid-on-skin-hydration-and-barrier-function-in-a-dynamic-three-dimensional-human-explant-model-S1545961616P0434X/

Sethi A, Kaur T, Malhotra SK, Gambhir ML. Moisturizers: The Slippery Road. Indian J Dermatol. 2016;61(3):279-287. https://doi.org/10.4103/0019-5154.182427