- Ceramides have been shown to be effective at restoring barrier function and increasing skin hydration when applied topically.
- Formulations containing cholesterol in concert with ceramides and other lipids have been shown to reduce skin dryness.
- Decreases in ceramide levels in the skin have been correlated with atopic dermatitis — a type of eczema that results in itchy, red, swollen, and cracked skin.
- Over the period of 6 weeks, ceramide application has led to significantly lower eczema severity scores compared to a control with no ceramides.
- Ceramides have been shown to exhibit similar effects as topical steroids which suggests that they possess anti-inflammatory properties.
- Phytosphingosine has been shown to play an important role in healthy skin by reducing inflammation, regulating cell growth, and possessing anti-bacterial properties.
