Hydroxyacetophenone

Ingredient

Hydroxyacetophenone

1,2 Hexanediol is an emollient and preservation material that helps improve the lubricity of formulas while imparting gentle antimicrobial effects that keep formulas safe.

Common Name

Hydroxyacetophenone

Category

Preservative

Benefits
  • Antimicrobial
  • Antioxidant
  • Soothing
  • Preservative
Performance Rating

Very Good

Chemical Structure

Hydroxyacetophenone is an aromatic ketone compound with the molecular formula C8H8O2. It consists of a benzene ring substituted with a hydroxyl group (-OH) and an acetyl group (-COCH3).

Quick Summary Benefits

  • Provides antimicrobial protection
  • Acts as an antioxidant
  • Offers soothing properties
  • Enhances product stability

Use & Background in Skincare

Hydroxyacetophenone is a multifunctional ingredient used in skincare formulations primarily as a preservative. It has gained popularity due to its ability to protect products from microbial contamination while offering additional benefits such as antioxidant and soothing properties.

Detailed Description

Hydroxyacetophenone is a versatile compound that has found its place in modern skincare formulations due to its multifaceted benefits. As a preservative, it plays a crucial role in maintaining product integrity by preventing the growth of harmful microorganisms. This function is particularly important in water-based formulations, which are more susceptible to microbial contamination [1].

Beyond its preservative capabilities, hydroxyacetophenone exhibits antioxidant properties. Antioxidants are vital in skincare as they help neutralize free radicals, which are unstable molecules that can cause oxidative stress and contribute to premature aging of the skin. By incorporating hydroxyacetophenone into skincare products, formulators can provide an additional layer of protection against environmental stressors [2].

Recent studies have also highlighted the soothing properties of hydroxyacetophenone. In a clinical trial, it was found to reduce skin redness and irritation, making it a valuable ingredient for sensitive skin formulations [3]. This multifunctionality makes hydroxyacetophenone an attractive option for cosmetic chemists looking to streamline their formulations while maintaining efficacy and skin benefits.

Comedogenicity

1 (Low) [4]

Sustainability Notes

Hydroxyacetophenone can be synthesized through various chemical processes. While it is not derived from natural sources, its production generally has a low environmental impact. Efforts are being made in the industry to develop more sustainable synthesis methods.

How It's Made

Hydroxyacetophenone is typically synthesized through the acetylation of phenol or the hydroxylation of acetophenone. These processes involve controlled chemical reactions in laboratory settings.

References

  1. Varvaresou, A., et al. (2009). Self-preserving cosmetics. International Journal of Cosmetic Science, 31(3), 163-175. https://doi.org/10.1111/j.1468-2494.2009.00492.x
  2. Rinnerthaler, M., et al. (2015). Oxidative stress in aging human skin. Biomolecules, 5(2), 545-589. https://doi.org/10.3390/biom5020545
  3. Kim, J., et al. (2018). Anti-inflammatory effects of hydroxyacetophenone isolated from Tagetes erecta L. in skin inflammation models. Molecules, 23(11), 2796. https://doi.org/10.3390/molecules23112796
  4. Fulton, J. E. (1989). Comedogenicity and irritancy of commonly used ingredients in skin care products. Journal of the Society of Cosmetic Chemists, 40, 321-333.

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