1,2 Hexanediol

Ingredient

1,2 Hexanediol

1,2 Hexanediol is an emollient and preservation material that helps improve the lubricity of formulas while imparting gentle antimicrobial effects that keep formulas safe.

Common Name

1,2 Hexanediol

Category

Preservative

Benefits
  • Moisturizing
  • Preservative
  • Solvent
  • Viscosity-controlling
Performance Rating

Very Good

Chemical Structure

1,2 Hexanediol is an organic compound with the molecular formula C6H14O2. It is a colorless liquid with a linear structure containing two hydroxyl groups (-OH) at the first and second carbon atoms of a six-carbon chain.

Quick Summary Benefits

  • Enhances product preservation
  • Improves moisture retention in the skin
  • Acts as an effective solvent for active ingredients
  • Helps control product viscosity

Use & Background in Skincare

1,2 Hexanediol is widely used in skincare formulations as a multifunctional ingredient. It primarily serves as a preservative, helping to extend the shelf life of products by inhibiting microbial growth. Additionally, it functions as a humectant and solvent, contributing to the overall efficacy and texture of skincare products.

Detailed Description

1,2 Hexanediol is a versatile compound that has gained popularity in the skincare industry due to its multifaceted benefits. As a preservative, it plays a crucial role in maintaining product integrity by preventing the growth of bacteria, yeasts, and molds. This function is particularly important in water-based formulations, which are more susceptible to microbial contamination [1].Beyond its preservative properties, 1,2 Hexanediol acts as a humectant, helping to attract and retain moisture in the skin. This moisturizing effect can contribute to improved skin hydration and a smoother, more supple complexion. Research has shown that humectants like 1,2 Hexanediol can enhance the skin's barrier function and reduce transepidermal water loss (TEWL) [2].Furthermore, 1,2 Hexanediol serves as an excellent solvent, aiding in the dissolution and delivery of various active ingredients in skincare formulations. This property enhances the overall efficacy of products by ensuring that beneficial compounds are properly dispersed and can penetrate the skin effectively. A study published in the International Journal of Cosmetic Science demonstrated that 1,2 Hexanediol could improve the solubility and stability of certain cosmetic ingredients, leading to enhanced product performance [3].

Comedogenicity

1,2 Hexanediol has a comedogenicity rating of 1 on a scale of 1-5, indicating that it is unlikely to clog pores or cause acne [4]. This low comedogenicity makes it suitable for use in a wide range of skincare products, including those formulated for acne-prone or sensitive skin.

Sustainability Notes

1,2 Hexanediol can be derived from both petrochemical and renewable sources. Some manufacturers are moving towards more sustainable production methods, using bio-based feedstocks to reduce environmental impact. However, the sustainability profile can vary depending on the specific sourcing and production processes employed.

How It's Made

1,2 Hexanediol is typically synthesized through the hydrogenation of adipic acid or its esters, followed by reduction to the diol form. It can also be produced from renewable resources such as corn or sugarcane through fermentation processes.

References

  1. Varvaresou A, et al. Self-preserving cosmetics. Int J Cosmet Sci. 2009;31(3):163-175. https://doi.org/10.1111/j.1468-2494.2009.00492.x
  2. Rawlings AV, Harding CR. Moisturization and skin barrier function. Dermatol Ther. 2004;17 Suppl 1:43-48. https://doi.org/10.1111/j.1396-0296.2004.04s1005.x
  3. Choi J, et al. Solubilization of water-insoluble ingredients in cosmetics by using 1,2-alkanediols. Int J Cosmet Sci. 2016;38(6):627-634. https://doi.org/10.1111/ics.12339
  4. Draelos ZD, DiNardo JC. A re-evaluation of the comedogenicity concept. J Am Acad Dermatol. 2006;54(3):507-512. https://doi.org/10.1016/j.jaad.2005.11.1058

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