• Allantoin has been shown to increase cell turnover by increasing cell proliferation. This increased growth reduces dullness and improves healing.
  • Has been demonstrated to reduce TEWL (transepidermal water loss) and can help to keep water in skin cells by acting like a sponge. The resulting effects help skin feel plump and soft.
  • Allantoin has been shown to induce wound healing by regulating the inflammatory response of the skin



  • Comparative Study of the Biological Activity of Allantoin and Aqueous Extract of the Comfrey Root. Phytother Research. 2015;29(8):1117-1122.
  • The effects of heat on skin barrier function and in vivo dermal absorption. International Journal of Pharmaceutics. 2014;464(1-2):145-151.
  • Profile of wound healing process induced by allantoin. Acta Cir Bras. 2010;25(5):460-466.

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