Butylene Glycol

Transparent Evidence Quality Rating

Discover the intuitive Voyager evidence quality rating system utilized for active ingredients contained in Voyager products.

Quality 1 // Rudimentary

Cell culture evidence

A cell culture is a collection of skin cells grown in a lab. It's a great way to test ingredients quickly.

Almost every ingredient starts its life under scientific scrutiny in the IGNITION grade. Not to be confused with ineffective, ingredients in IGNITION present as having promise, but not unequivocal efficacy on your skin. 

Examples include some peptides, novel delivery technologies, and new retinoids.

Quality 2 // Primary

Skin model evidence

Skin models are recreated structures of the skin that can be used to test systematic performance of an ingredient. There are two types: ex-vivo (inside an organism such as a fish) and in-vitro* (outside of an organism). 

Skin model evidence can suggest multifunctional properties of an ingredient and demonstrate greater efficacy than a culture. 

*Voyager does not participate nor condone animal studies. 

Quality 3 // Established

Early evidence in human skin

Human skin studies demonstrate efficacy by measuring properties of the skin (such as moisture, wrinkle depth, and oil production) in the presence an ingredient.

Participants in trials typically apply the ingredient for a number of weeks and are evaluated by scientists at multiple points during the trial. 

Quality 4 // Exceptional

Established evidence of efficacy in human skin

Study design is paramount to the quality of evidence. Established evidence is demonstrated with exceptional study design that often involves placebo control. Placebo control compares the effects of the ingredient with and without its presence. 

Often participants in the trial are blinded so that they don't know if they're receiving the ingredient or the placebo. This helps reduce bias in the trial. 

Results of trials of ORBIT quality are often published in scientific journals such as the Journal of the American Academy of Dermatology

Quality 5 // Extraordinary

Evidence of efficacy in Voyager product as sold

The gold standard of an ingredient is demonstrated efficacy in the product as sold. The composition of every product is different. Other ingredients in the product may improve or reduce efficacy of the ingredient being studied.

For example: the presence of phospholipids in Dark Side of the Moon help to increase the penetration of fat soluble antioxidants resveratrol and ubiquinone (CoQ10). The efficacy of these ingredients is increased in the formula compared to the same concentration applied without phospholipids.

Studies of complete products are arduous, but the best way to demonstrate that the ingredients in the product actually work in the product.